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apml differentiation fatty hematology hepatology liver obgyn oncology pathophysiology pregnancy
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... vomiting, abdominal pain ... Cr, ↓Glucose, ↓PLT ... infiltration) Differential ... Pregnancy #hepatology #obstetrics
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... initiation • Differential ... organ dysfuxtion, ICU ... fluid overload, PCC ... #management #hematology
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