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algorithm causes injury classification hematology management abnormal aflp anemia apml biliary cholangitis cirrhosis differentiation elevated elevation fatty gap globulin hepatitis
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Liver Injury - Differential ... Diagnosis Hepatocellular ... Malignancy, 1° PBC ... , 1° PSC, Cystic ... #hepatology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... Ducts - PBC ... , PSC, Alcoholic ... Biliary stricture, PSC
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... Autoimmune hepatitis, PBC ... , PSC, IgG4, HLH ... stone, Malignancy, PBC ... , PSC, Cystic fibrosis
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Pathophysiology ... cholestasis → Cirrhosis/Liver ... or higher • Liver ... bile ducts Differential ... #workup #hepatology
Posterior Cruciate Ligament (PCL) Injury: Pathogenesis and Clinical Findings Classification of PCL Iniuries • Partial: Translation <
Posterior Cruciate ... Ligament (PCL) ... #Injury #MSK #Sports ... #pathophysiology ... classification #diagnosis
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... Cr, ↓Glucose, ↓PLT ... infiltration) Differential ... Diagnosis: Viral ... #Pregnancy #hepatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
ATRA treatment Pathophysiology ... • Rare: DAH, acute ... initiation • Differential ... fluid overload, PCC ... #management #hematology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
- Differential ... www.ncbi.nlm.nih.gov/pmc ... tests before beginning ... cardiac output - Acute ... peritonitis - Acute
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Sarcoidosis) • Liver ... autoimmune hepatitis, PBC ... , PSC, Viral hepatitis ... Gap #ProteinGap #differential ... #diagnosis #hematology
Anemia of Hospitalization - Pathophysiology Why does the Hgb/Hct drop in the first two days during hospitalization? Interestingly,
www.ncbi.nlm.nih.gov/pmc ... www.ncbi.nlm.nih.gov/pmc ... www.ncbi.nlm.nih.gov/pmc ... blood loss or acute ... #differential #
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