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diagnosis hepatology acidosis aflp aih alcoholic alkaline alp autoimmune classification fatty gap globulin hbv hematology hepatitisb hepbv indications lactate lactic
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute ... Liver Injury - Differential ... , 1° PSC, Cystic ... #Injury #Differential ... #Acute #algorithm
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... , PBC, PSC, IgG4 ... stone, Malignancy, PBC ... , PSC, Cystic fibrosis ... #injury #hepatitis
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
- Differential ... Diagnosis Algorithm ... Intestine - Other causes ... biliary Cholangitis (PBC ... Infiltrative diseases - PSC
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
subclinical disease to acute ... liver failure ... injury, though ... reported (eg AIH-PBC ... (rare) - IgG Elevation
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... - Differential ... Bile Ducts • PSC ... • Alcoholic hepatitis ... #Causes
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... = nonspecific (nausea ... Cr, ↓Glucose, ↓PLT ... infiltration) Differential ... Diagnosis: Viral Hepatitis
Hepatitis B - Treatment Indications Treatment not indicated: • Immune tolerant state - HBe-Ag detectable, high HBV
Hepatitis B - Treatment ... Presence of CP or PC ... injury (INR > 2 ... liver failure ... #Indications #management
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
Acidosis - Differential ... www.ncbi.nlm.nih.gov/pmc ... or renal injury ... Injury: • Reduced ... #Differential #
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Viral infections (acute ... Sarcoidosis) • Liver ... , PBC, PSC, Viral ... inflammation (acute ... Gap #ProteinGap #differential
Alcoholic Hepatitis - Management Algorithm Assess Eligibility for Treatment: - Maddrey Discriminant Function ≥ (or possibly MELD
- Management Algorithm ... exclude other causes ... kidney injury with ... HCV, DILI, HCC, ... #Management #Algorithm
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