8 results
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
Diagnosis Algorithm ... Intestine - Other causes ... Cholangitis (PBC ... Infiltrative diseases - PSC ... #hepatology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Causes of Acute ... Liver Injury - Differential ... Malignancy, 1° PBC ... , 1° PSC, Cystic ... #Acute #algorithm
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... Autoimmune hepatitis, PBC ... , PSC, IgG4, HLH ... stone, Malignancy, PBC ... , PSC, Cystic fibrosis
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
intralobular bile ducts causes ... Labs: • Alkaline ... bile ducts Differential ... cholangitis #diagnosis #workup ... #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Diagnosis Algorithm ... Bile Ducts • PSC ... Duct Stone • Biliary ... Others #LFTs #Hepatology ... #Causes
Acute Altered Mental Status - Rapid Response Management

1) Ask while en route: vitals, hyper/hypoactive, POC glucose,
Acute Altered Mental ... hyper/hypoactive, POC ... Diagnosis and Workup ... the underlying cause ... encephalopathy #differential
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Albumin > 4) Work-up ... autoimmune hepatitis, PBC ... , PSC, Viral hepatitis ... inflammation (acute ... Gap #ProteinGap #differential
Alcoholic Hepatitis - Management Algorithm
Assess Eligibility for Treatment:
 - Maddrey Discriminant Function ≥ (or possibly MELD
Algorithm Assess ... exclude other causes ... kidney injury with ... HCV, DILI, HCC, ... #Algorithm #hepatology