22 results
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Diagnosis Algorithm ... Ducts - PBC ... , PSC, Alcoholic ... Biliary stricture, PSC
Algorithm and Causes of an Elevated Hemidiaphragm #Diagnosis #Radiology #EM #IM #PCC #Elevated #Hemidiaphragm #ElevatedHemidiaphragm #Diaphragm
Algorithm and Causes ... Hemidiaphragm #Diagnosis ... #Radiology #EM ... #IM #PCC #Elevated ... ElevatedHemidiaphragm #Diaphragm #Differential
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... Diagnosis Algorithm ... Bile Ducts • PSC ... #Diagnosis #Algorithm ... #Causes
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Diagnosis Algorithm ... , PSC, IgG4, HLH ... stone, Malignancy, PBC ... , PSC, Cystic fibrosis ... #diagnosis #algorithm
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
Diagnosis Algorithm ... Intestine - Other causes ... biliary Cholangitis (PBC ... Infiltrative diseases - PSC ... #Diagnosis #Algorithm
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
intralobular bile ducts causes ... cholestasis → Cirrhosis/Liver ... obstruction • ALP ... or higher • Liver ... bile ducts Differential
Primary Biliary Cirrhosis - Diagnosis Algorithm
Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort
Signs: Jaundice, Xanthelasmata, Hepatomegaly
Associated history:
PBC if 2/3 criteria ... Elevated ALP 2. ... Liver biopsy findings ... consistent with PBC ... #PBC #Primary
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Liver Injury - Differential ... Malignancy, 1° PBC ... , 1° PSC, Cystic ... #Diagnosis #Causes ... #Acute #algorithm
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
disease to acute liver ... hepatocellular pattern of liver ... reported (eg AIH-PBC ... IgG typically elevated ... Anti-LKM & Anti-ALC
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... gastric bypass), LFT ... (liver disease) ... not required in all ... #Diagnosis #Causes