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differential algorithm treatment cholangitis foamed hematology pharmacology primary abnormal altered ams apml biliary cardiology challenges chf clinical comparison criteria crystalloids
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Ducts - PBC ... , PSC, Alcoholic ... Congenital, Others, Cirrhosis ... Biliary stricture, PSC ... Burak @kwburak #LFTs
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Bile Ducts • PSC ... Infiltrative • Cirrhosis ... • Others #LFTs ... #Hepatology #LiverEnzymes ... #Algorithm #Causes
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
(PBC) - Summary ... PBC Epidemiology ... 30-65 years PBC ... intralobular bile ducts causes ... #hepatology
The 6 C’s of Primary Sclerosing Cholangitis (PSC) PSC is a chronic, cholestatic, immune-mediated disease characterized by
asymptomatic at diagnosis ... liver disease management ... #Cholangitis #diagnosis ... #management #summary ... #Hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Algorithm Vascular Causes ... Autoimmune hepatitis, PBC ... , PSC, IgG4, HLH ... stone, Malignancy, PBC ... , PSC, Cystic fibrosis
Hepatitis B - Treatment Indications Treatment not indicated: • Immune tolerant state - HBe-Ag detectable, high HBV
Presence of CP or PC ... Family history of cirrhosis ... or fibrosis • Cirrhosis ... #Indications #management ... #hepatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
opacities • Diagnosis ... organ dysfuxtion, ICU ... : Diuresis for fluid ... overload, PCC to ... #management #hematology
Sepsis - Diagnosis and Management Life-threatening organ dysfunction caused by a dysregulated host response to infection SEPTIC SHOCK
Sepsis - Diagnosis ... organ dysfunction caused ... antibiotics 2 Initial fluid ... #SIRS #criticalcare ... #icu
Fluid Responsiveness and Fluid Tolerance Testing - OnePager Summary Fluid resuscitation can be beneficial when required or
measurement of CO via a PAC ... cardiac output causes ... Tolerance #testing #diagnosis ... #criticalcare # ... comparison #challenges #management
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Liver disease: Cirrhosis ... autoimmune hepatitis, PBC ... , PSC, Viral hepatitis ... #differential #diagnosis ... #hematology
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