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treatment differential algorithm cholangitis encephalopathy hematology liver primary syndrome altered ams apml biliary chagas challenges cheatsheet classification comparison complications coronavirus
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
(PBC) - Summary ... PBC Epidemiology ... 30-65 years PBC ... intralobular bile ducts causes ... #hepatology
End Stage Liver Disease (Cirrhosis) - Complications • Ascites • Esophageal Varices • Hepatic
Liver Disease (Cirrhosis ... Hepatocellular Carcinoma (HCC ... Complications #diagnosis ... #management #summary ... #hepatology
The 6 C’s of Primary Sclerosing Cholangitis (PSC) PSC is a chronic, cholestatic, immune-mediated disease characterized by
asymptomatic at diagnosis ... liver disease management ... #Cholangitis #diagnosis ... #management #summary ... #Hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
- Differential Diagnosis ... Bile Ducts • PSC ... Infiltrative • Cirrhosis ... Others #LFTs #Hepatology ... #Algorithm #Causes
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Algorithm Vascular Causes ... Autoimmune hepatitis, PBC ... , PSC, IgG4, HLH ... stone, Malignancy, PBC ... , PSC, Cystic fibrosis
Hepatitis B - Treatment Indications Treatment not indicated: • Immune tolerant state - HBe-Ag detectable, high HBV
Presence of CP or PC ... Family history of cirrhosis ... or fibrosis • Cirrhosis ... #Indications #management ... #hepatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
opacities • Diagnosis ... • Differential Diagnosis ... organ dysfuxtion, ICU ... fluid overload, PCC ... #management #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Cytopenia +++ (Plt ... Drugs, Unknown cause ... of emergency, ICU ... #management #treatment ... #summary #rheumatology
Hepatic Encephalopathy - Diagnosis and Management Summary Definition: • Alteration in brain function manifested by neuropsychiatric symptoms
and Management ... Summary Definition ... Prevalence: At cirrhosis ... #Management #treatment ... #hepatology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Liver disease: Cirrhosis ... autoimmune hepatitis, PBC ... , PSC, Viral hepatitis ... #differential #diagnosis ... #hematology
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