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differential treatment algorithm primary encephalopathy hematology liver psc sclerosing syndrome alkaline alp altered ams apml biliary cancer chagas challenges cheatsheet
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
(PBC) - Summary ... PBC Epidemiology ... intralobular bile ducts causes ... #PBC #cholangitis ... #hepatology
Primary sclerosing cholangitis (PSC) - Malignancy Screening and Surveillance Recommendations Cholangiocarcinoma - Annual US or
(PSC) - Malignancy ... (with cirrhosis ... #PSC #Malignancy ... Gastroenterology #Management ... #Diagnosis
The 6 C’s of Primary Sclerosing Cholangitis (PSC) PSC is a chronic, cholestatic, immune-mediated disease characterized by
(PSC) PSC is a ... asymptomatic at diagnosis ... liver disease management ... #diagnosis #management ... #summary #Hepatology
End Stage Liver Disease (Cirrhosis) - Complications • Ascites • Esophageal Varices • Hepatic
Liver Disease (Cirrhosis ... Hepatocellular Carcinoma (HCC ... Complications #diagnosis ... #management #summary ... #hepatology
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
Intestine - Other causes ... Primary biliary Cholangitis ... (PBC) - Other ... Infiltrative diseases - PSC ... #Algorithm #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
- Differential Diagnosis ... Bile Ducts • PSC ... Infiltrative • Cirrhosis ... Others #LFTs #Hepatology ... #Algorithm #Causes
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Algorithm Vascular Causes ... Autoimmune hepatitis, PBC ... , PSC, IgG4, HLH ... stone, Malignancy, PBC ... , PSC, Cystic fibrosis
Hepatitis B - Treatment Indications Treatment not indicated: • Immune tolerant state - HBe-Ag detectable, high HBV
Presence of CP or PC ... Family history of cirrhosis ... or fibrosis • Cirrhosis ... #Indications #management ... #hepatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
opacities • Diagnosis ... • Differential Diagnosis ... organ dysfuxtion, ICU ... fluid overload, PCC ... #management #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Cytopenia +++ (Plt ... Drugs, Unknown cause ... of emergency, ICU ... #management #treatment ... #summary #rheumatology
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