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hepatology algorithm differential primary pbc rheumatology cholangitis hepatitis lfts summary syndrome abnormal aih alkaline apml autoimmune cardiology differentiation elevated elevation
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Ducts - PBC ... , PSC, Alcoholic ... Congenital, Others, Cirrhosis ... - CBD stone, Biliary ... stricture, PSC,
Primary Biliary Cirrhosis - Diagnosis Algorithm Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort Signs: Jaundice, Xanthelasmata, Hepatomegaly Associated history:
Cirrhosis - Diagnosis ... PBC if 2/3 criteria ... consistent with PBC ... #PBC #Primary ... #Biliary #Cirrhosis
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Cirrhosis (PBC) ... intralobular bile ducts causes ... obstruction • ALP ... #Cirrhosis #PBC ... #workup #hepatology
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
- Differential Diagnosis ... Intestine - Other causes ... Cholangitis (PBC ... Infiltrative diseases - PSC ... #Algorithm #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Algorithm Vascular Causes ... Autoimmune hepatitis, PBC ... , PSC, IgG4, HLH ... stone, Malignancy, PBC ... , PSC, Cystic fibrosis
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
- Differential Diagnosis ... Bile Ducts • PSC ... Infiltrative • Cirrhosis ... Duct Stone • Biliary ... #Algorithm #Causes
The 6 C’s of Primary Sclerosing Cholangitis (PSC) PSC is a chronic, cholestatic, immune-mediated disease characterized by
to multi-focal biliary ... asymptomatic at diagnosis ... #Cholangitis #diagnosis ... #management #summary ... #Hepatology
Hepatitis B - Treatment Indications Treatment not indicated: • Immune tolerant state - HBe-Ag detectable, high HBV
Presence of CP or PC ... Family history of cirrhosis ... or fibrosis • Cirrhosis ... #Indications #management ... #hepatology
Primary Biliary Cirrhosis - Management A. Initiate therapy - Initiate 1st line therapy with UDCA (13-15
Cirrhosis - Management ... line therapy if ALP ... survey disease #PBC ... #Cirrhosis #Management ... #Treatment #hepatology
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
reported (eg AIH-PBC ... Anti-LKM & Anti-ALC ... Hepatitis (eg Viral) Management ... regarding need for treatment ... #Management #Hepatology
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