9 results
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
Alkaline Phosphatase (ALP ... Algorithm ALP ... - Increased ALP ... (PBC) - Other ... Infiltrative diseases - PSC
Primary sclerosing cholangitis (PSC) - Malignancy Screening and Surveillance Recommendations 

Cholangiocarcinoma 
 - Annual US or
Primary sclerosing ... cholangitis (PSC ... q 6 months +/- AFP ... #PSC #Malignancy ... Gastroenterology #Management
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
intralobular bile ducts causes ... obstruction • ALP ... or higher • Liver ... #cholangitis #diagnosis ... #workup #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Algorithm Vascular Causes ... Autoimmune hepatitis, PBC ... , PSC, IgG4, HLH ... stone, Malignancy, PBC ... , PSC, Cystic fibrosis
Algorithm for the Diagnosis of Primary Biliary Cholangitis (PBC). 

US, ultrasound; MRCP, magnetic resonance cholangiopancreatography; ALP,
of Primary Biliary ... Cholangitis (PBC ... cholangiopancreatography; ALP ... #PBC #Algorithm ... #Diagnosis #Hepatology
Primary Biliary Cirrhosis - Diagnosis Algorithm
Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort
Signs: Jaundice, Xanthelasmata, Hepatomegaly
Associated history:
PBC if 2/3 criteria ... Elevated ALP 2. ... Liver biopsy findings ... consistent with PBC ... #PBC #Primary
The 6 C’s of Primary Sclerosing Cholangitis (PSC)
PSC is a chronic, cholestatic, immune-mediated disease characterized by
The 6 C’s of Primary ... (PSC) PSC is a ... disease management ... #Cholangitis #diagnosis ... #Hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... • Pregnancy - AFLP ... Bile Ducts • PSC ... Others #LFTs #Hepatology ... #Algorithm #Causes
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... = nonspecific (nausea ... Cr, ↓Glucose, ↓PLT ... iMedEducation #AFLP ... Pregnancy #hepatology