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differential algorithm hematology injury treatment aflp aih autoimmune biliary cholangitis cirrhosis coagulation ddxof diaphragm dic disseminated elevated elevatedhemidiaphragm fatty gap
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute ... Malignancy, 1° PBC ... , 1° PSC, Cystic ... #Causes #Acute ... #algorithm #hepatology
Algorithm and Causes of an Elevated Hemidiaphragm #Diagnosis #Radiology #EM #IM #PCC #Elevated #Hemidiaphragm #ElevatedHemidiaphragm #Diaphragm
Algorithm and Causes ... Hemidiaphragm #Diagnosis ... #Radiology #EM ... #IM #PCC #Elevated
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... of Acute Liver ... , PBC, PSC, IgG4 ... stone, Malignancy, PBC ... , PSC, Cystic fibrosis
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
intralobular bile ducts causes ... cholestasis → Cirrhosis/Liver ... or higher • Liver ... : • Viral hepatitis ... #workup #hepatology
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
subclinical disease to acute ... liver failure ... reported (eg AIH-PBC ... (eg Viral) Management ... #Management #Hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... Bile Ducts • PSC ... • Alcoholic hepatitis ... Others #LFTs #Hepatology ... #Algorithm #Causes
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... = nonspecific (nausea ... Cr, ↓Glucose, ↓PLT ... : Viral Hepatitis ... #Pregnancy #hepatology
Hepatitis B - Treatment Indications Treatment not indicated: • Immune tolerant state - HBe-Ag detectable, high HBV
Hepatitis B - Treatment ... Presence of CP or PC ... liver failure ... #Indications #management ... #hepatology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Viral infections (acute ... Sarcoidosis) • Liver ... , PBC, PSC, Viral ... inflammation (acute ... #differential #diagnosis
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
malignancy (Especially acute ... DIC • Severe Liver ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
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