13 results
diagnosis hepatology algorithm hematology cirrhosis classification elevation hepatitis lfts oncology primary acidosis aih alkaline autoimmune cholangitis differentiation elevated gap globulin
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... Ducts - PBC ... , PSC, Alcoholic ... stricture, PSC,
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Algorithm Vascular Causes ... Autoimmune hepatitis, PBC ... , PSC, IgG4, HLH ... stone, Malignancy, PBC ... , PSC, Cystic fibrosis
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
) Elevation - Differential ... Intestine - Other causes ... Cholangitis (PBC ... Infiltrative diseases - PSC ... - Other biliary
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Cirrhosis (PBC) ... - Summary PBC ... 30-65 years PBC ... failure PBC ... • Fatigue PBC
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... - Differential ... Bile Ducts • PSC ... Duct Stone • Biliary ... Diagnosis #Algorithm #Causes
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Incidence: common in APL ... Triggers: ATRA treatment ... initiation • Differential ... fluid overload, PCC ... #diagnosis #management
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
disease to acute liver ... reported (eg AIH-PBC ... upper limit of normal ... Anti-LKM & Anti-ALC ... regarding need for treatment
Hepatitis B - Treatment Indications Treatment not indicated: • Immune tolerant state - HBe-Ag detectable, high HBV
ALT Treatment ... Presence of CP or PC ... infection with severe liver ... mg/dL) or acute liver ... #Indications #management
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Sarcoidosis) • Liver ... autoimmune hepatitis, PBC ... , PSC, Viral hepatitis ... chain assay • An abnormal ... Gap #ProteinGap #differential
Primary Biliary Cirrhosis - Management A. Initiate therapy - Initiate 1st line therapy with UDCA (13-15
Primary Biliary ... line therapy if ALP ... 1.5x ULN and/or abnormal ... survey disease #PBC ... #Treatment #hepatology
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