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diagnosis differential hepatology injury liver acute anemia aplastic common cvid erythematosus extravascular gap globulin hemolysis hypogammaglobulinemia immunodeficiency immunology intravascular lfts
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute ... Other: NAFLD, Autoimmune ... Malignancy, 1° PBC ... , 1° PSC, Cystic ... #Acute #algorithm
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
• Ischemia • Autoimmune ... • Drugs • AIH ... Bile Ducts • PSC ... • Alcoholic hepatitis ... #Causes
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
Autoimmune Hepatitis ... been reported (eg AIH-PBC ... (eg Viral) Management ... #Hepatitis #AIH ... #Hepatology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... Differential Diagnosis Algorithm ... • Alloimmune ... • PCH ... #Causes #Hematology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Vascular Causes ... : Autoimmune hepatitis ... , PBC, PSC, IgG4 ... stone, Malignancy, PBC ... , PSC, Cystic fibrosis
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Cirrhosis, ETOH, autoimmune ... hepatitis, PBC, ... PSC, Viral hepatitis ... gastric tumors • Hematology ... differential #diagnosis #hematology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... Liver diseases and hepatitis ... : Pneumonia • Autoimmune ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... disease • Non-autoimmune ... Noninfectious hepatitis ... Antiribosomal P, APLA, PAC ... : • AIHA 10% •
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia Clinical ... and petechiae Causes ... Aplastic Anemia: - Hepatitis ... Anemia #oncology #hematology ... #diagnosis #management
Monkeypox What? Monkeypox virus belongs to the family Poxviridae, subfamily Chordopoxvirinae, and genus orthopoxvirus Viral zoonotic disease that is
disease that is caused ... three weeks Clinical ... chain reaction (PCR ... MPOX #Diagnosis #Management ... #Dermatology
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