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diagnosis differential algorithm anemia hemeonc syndrome workup agglutinin aih aplastic apml biliary cholangitis chronic cirrhosis classification cll cold common cvid
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
and Platelet Disorders ... smear, HIV/HCV testing ... function test, ANA ... or if a primary hematologic ... #Workup #hematology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
) - Summary PBC ... intralobular bile ducts causes ... Proximal limb muscle wasting ... patients • +ANA ... diagnosis #workup #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
• Ischemia • Autoimmune ... Bile Ducts • PSC ... • Cirrhosis (any ... Others #LFTs #Hepatology ... Diagnosis #Algorithm #Causes
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
Autoimmune Hepatitis ... reported (eg AIH-PBC ... : Auto-Nuclear ANA ... AIH #Diagnosis #Management ... #Hepatology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Viral infection, autoimmune ... disorder or lymphoid ... Positive Coombs testing ... CLL (older) • Autoimmune ... hemolytic #anemia #hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Connective tissue disorders ... hepatitis, PBC, ... PSC, Viral hepatitis ... gastric tumors • Hematology ... differential #diagnosis #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
leukemia in adults • Disorder ... lymphadenopathy and ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc ... #diagnosis #management
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
cell adhesion and ... : leukocytosis and ... fluid overload, PCC ... APML #diagnosis #management ... #hematology #oncology
Post-Transplantation Lymphoproliferative Disorders (PTLD) Definition: Lymphoid and/or plasmacytic proliferations that occur as a result of immunosuppression in
Lymphoproliferative Disorders ... symptoms, unexplained hematologic ... to 50% of PTLD cases ... #oncology #diagnosis ... #management #transplant
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. Step 1: In the patient with
elevated, HFE gene testing ... hematologic disorders ... If other causes ... algorithm #diagnosis #management ... #hepatology #gastroenterology
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