12 results
diagnosis hepatology differential algorithm hepatitis classification liver treatment acidosis acute aih alcoholic anemia aplastic biliary elevation gap globulin hemophagocytic hepatitisb
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Algorithm Vascular Causes ... , HBV, HCV, HEV, ... , PBC, PSC, IgG4 ... stone, Malignancy, PBC ... , PSC, Cystic fibrosis
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute ... Liver Injury - Differential ... Other: NAFLD, Autoimmune ... Malignancy, 1° PBC ... , 1° PSC, Cystic
Hepatitis B - Treatment Indications Treatment not indicated: • Immune tolerant state - HBe-Ag detectable, high HBV
Presence of CP or PC ... or fibrosis • Cirrhosis ... with severe liver injury ... #Indications #management ... #hepatology
Primary Biliary Cirrhosis - Pathophysiology Environmental Risk Factors: Geographic location, Smoking, Microbial triggers, Xenobiotics, Nail polish Epigentics Risk
Primary Biliary Cirrhosis ... relative with PBC ... T-cell mediated BEC injury ... Cholestasis #PBC ... Pathophysiology #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
• Ischemia • Autoimmune ... Bile Ducts • PSC ... Infiltrative • Cirrhosis ... Others #LFTs #Hepatology ... Diagnosis #Algorithm #Causes
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
Autoimmune Hepatitis ... pattern of liver injury ... reported (eg AIH-PBC ... AIH #Diagnosis #Management ... #Hepatology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
, HBV, EBV, VZV, ... Liver disease: Cirrhosis ... , ETOH, autoimmune ... hepatitis, PBC, ... PSC, Viral hepatitis
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Marrow (Toxic injury ... and petechiae Causes ... Aplastic #Anemia #oncology ... #hematology #diagnosis ... #management
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Cytopenia +++ (Plt ... solid cancers • Autoimmune ... Drugs, Unknown cause ... Lymphohistiocytosis #diagnosis #management ... treatment #summary #rheumatology
Alcoholic Hepatitis - Management Algorithm Assess Eligibility for Treatment: - Maddrey Discriminant Function ≥ (or possibly MELD
Alcoholic Hepatitis - Management ... exclude other causes ... - Acute kidney injury ... HCV, DILI, HCC, ... #Algorithm #hepatology
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