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differential algorithm liver treatment injury biliary cholangitis cirrhosis hemophagocytic hepatitis hlh intravascular lymphohistiocytosis pbc rheumatology summary syndrome aflp aih alkaline
Primary Biliary Cirrhosis - Diagnosis Algorithm Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort Signs: Jaundice, Xanthelasmata, Hepatomegaly Associated history:
Primary Biliary ... PBC if 2/3 criteria ... consistent with PBC ... #PBC #Primary ... #Algorithm #hepatology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute ... Malignancy, 1° PBC ... , 1° PSC, Cystic ... #Causes #Acute ... #algorithm #hepatology
Causes of Severe Acute Liver Injury - Ichemic hepatitis - Acute biliary obstruction - Drug-Induced liver
Causes of Severe ... Hepatitis - Autoimmune ... Hemochromatosis - Primary ... #Causes #Differential ... #Hepatology #Diagnosis
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
Intestine - Other causes ... - Drugs - Primary ... biliary Cholangitis (PBC ... Infiltrative diseases - PSC ... #Algorithm #hepatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Cirrhosis (PBC) ... - Summary PBC ... 30-65 years PBC ... intralobular bile ducts causes ... #workup #hepatology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... Thrombocytosis): • Acute ... disorders (e.g. autoimmune ... Post-splenectomy Primary ... #Causes #hematology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Algorithm Vascular Causes ... , PBC, PSC, IgG4 ... stone, Malignancy, PBC ... , PSC, Cystic fibrosis ... #algorithm #hepatology
Causes of Eosinophilia - Differential Diagnosis Bugs: - Fungus (aspergillosis) - Viral (HIV) - Ectoparasites (scabies, myiasis)
Causes of Eosinophilia ... - Differential Diagnosis ... (vasculitis / autoimmune ... Mastocytosis - Acute ... #Causes #hematology
The 6 C’s of Primary Sclerosing Cholangitis (PSC) PSC is a chronic, cholestatic, immune-mediated disease characterized by
The 6 C’s of Primary ... asymptomatic at diagnosis ... #Primary #Sclerosing ... #management #summary ... #Hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
- Differential Diagnosis ... • Ischemia • Autoimmune ... Bile Ducts • PSC ... Others #LFTs #Hepatology ... #Algorithm #Causes
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