28 results
Cholestatic Liver Disease: Primary Biliary Cirrhosis vs Primary Sclerosing Cholangitis

#pathophysiology #pbc #psc #hepatology #comparison
Primary Biliary Cirrhosis ... pathophysiology #pbc ... #psc #hepatology
Split, Fractured Patella on Knee Exam

30 years old male, 10 years post motorbike accident.  Split,
tears of ACL , PCL ... , PLC Via @ ... Patella #Knee #PhysicalExam ... clinical #video #msk
Posterolateral Corner (PLC) Injury - Posterolateral Drawer Test
Injury to the posterolateral corner (PLC) is difficult to
Posterolateral Corner (PLC ... posterolateral corner (PLC ... posterolateral corner (PLC ... Clinical #Video #PhysicalExam ... Knee #Posterior #msk
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Ducts - PBC ... , PSC, Alcoholic ... Congenital, Others, Cirrhosis ... Biliary stricture, PSC ... Algorithm #diagnosis #hepatology
Primary Biliary Cirrhosis - Pathophysiology
Environmental Risk Factors: Geographic location, Smoking, Microbial triggers, Xenobiotics, Nail polish
Epigentics Risk
Primary Biliary Cirrhosis ... relative with PBC ... T-cell mediated BEC injury ... Cholestasis #PBC ... Pathophysiology #hepatology
Primary Biliary Cirrhosis - Diagnosis Algorithm
Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort
Signs: Jaundice, Xanthelasmata, Hepatomegaly
Associated history:
Primary Biliary Cirrhosis ... pregnancy Diagnose PBC ... consistent with PBC ... #PBC #Primary ... Diagnosis #Algorithm #hepatology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
(PBC) - Summary ... PBC Epidemiology ... 30-65 years PBC ... • Fatigue PBC ... diagnosis #workup #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Autoimmune hepatitis, PBC ... , PSC, IgG4, HLH ... stone, Malignancy, PBC ... , PSC, Cystic fibrosis ... hepatitis: < 1 • Cirrhosis
The 6 C’s of Primary Sclerosing Cholangitis (PSC)
PSC is a chronic, cholestatic, immune-mediated disease characterized by
) PSC is a chronic ... • CIRRHOSIS - ... Progression to cirrhosis ... decompensated cirrhosis ... management #summary #Hepatology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
of Acute Liver Injury ... Malignancy, 1° PBC ... , 1° PSC, Cystic ... Sophia_Hayes_MD #Liver #Injury ... Acute #algorithm #hepatology