5 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Attempt if high risk ... Imaging: CXR- pulmonary ... initiation • Differential ... fluid overload, PCC ... diagnosis #management #hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Cirrhosis, ETOH, autoimmune ... hepatitis, PBC, ... PSC, Viral hepatitis ... gastric tumors • Hematology ... #diagnosis #hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... rheumatologic diseases ... Antiribosomal P, APLA, PAC ... Thrombosis highest risk ... Erythematosus #Diagnosis #Rheumatology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma Risk ... • History of EBV ... Immunosuppression • Autoimmune ... Immunohistochemical studies (to differentiate ... classification #hematology
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
- Differential ... • ANA < 20 % IBM ... Other Diseases: • PBC ... Myositis #Myopathy #rheumatology ... #differential #