16 results
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
- Differential Diagnosis ... Ducts - PBC ... , PSC, Alcoholic ... - CBD stone, Biliary ... stricture, PSC,
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
- Differential Diagnosis ... Cholangitis (PBC ... Infiltrative diseases - PSC ... - Other biliary ... #Algorithm #hepatology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Cirrhosis (PBC) ... - Summary PBC ... obstruction • ALP ... #cholangitis #diagnosis ... #workup #hepatology
Algorithm for the Diagnosis of Primary Biliary Cholangitis (PBC). 

US, ultrasound; MRCP, magnetic resonance cholangiopancreatography; ALP,
of Primary Biliary ... Cholangitis (PBC ... cholangiopancreatography; ALP ... #Cholangitis #PBC ... #Hepatology
The 6 C’s of Primary Sclerosing Cholangitis (PSC)
PSC is a chronic, cholestatic, immune-mediated disease characterized by
(PSC) PSC is a ... to multi-focal biliary ... asymptomatic at diagnosis ... #diagnosis #management ... #summary #Hepatology
Primary Biliary Cirrhosis - Diagnosis Algorithm
Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort
Signs: Jaundice, Xanthelasmata, Hepatomegaly
Associated history:
PBC if 2/3 criteria ... Elevated ALP 2. ... consistent with PBC ... #PBC #Primary ... #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential Diagnosis ... Autoimmune hepatitis, PBC ... , PSC, IgG4, HLH ... stone, Malignancy, PBC ... , PSC, Cystic fibrosis
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
- Differential Diagnosis ... Bile Ducts • PSC ... Duct Stone • Biliary ... Others #LFTs #Hepatology ... #Differential #Diagnosis
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
pericarditis • Hepatic: PBC ... (primary biliary ... cholangitis) overlap ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
reported (eg AIH-PBC ... , AIH diagnosis ... Anti-LKM & Anti-ALC ... regarding need for treatment ... #Management #Hepatology