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diagnosis algorithm biliary cirrhosis hematology liver pbc primary rheumatology workup abnormal aflp alkaline autoimmune causes cholangitis disorders elevation enzymes evaluation
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
) Elevation - Differential ... Most common symptoms ... - Bone symptoms ... #Elevation #Differential ... Diagnosis #Algorithm #hepatology
Primary Biliary Cirrhosis - Diagnosis Algorithm Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort Signs: Jaundice, Xanthelasmata, Hepatomegaly Associated history:
Diagnosis Algorithm Symptoms ... quadrant discomfort Signs ... of autoimmune disease ... Elevated ALP 2. ... Diagnosis #Algorithm #hepatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Signs and Symptoms ... but elevated as disease ... obstruction • ALP ... bile ducts Differential ... diagnosis #workup #hepatology
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
postpartum): • Initial symptoms ... abdominal pain, headache ... Cr, ↓Glucose, ↓PLT ... infiltration) Differential ... Liver #Pregnancy #hepatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
rapid onset of symptoms ... Symptoms: • Malaise ... extramedullary disease ... Blast Phase: • Headaches ... #Leukemia #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Platelet Disorders - Differential ... PT, aPTT(liver disease ... pylori test (GI symptoms ... bypass), LFT (liver disease ... not required in all
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
suspicious clinical symptoms ... /signs should be ... ALP, alkaline phosphatase ... Abnormal #Algorithm #Hepatology ... Liver #Enzymes #Differential
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Presentation: Systemic Symptoms ... purpura: Strong sign ... 50 years • New headache ... • Progressive symptoms ... of headache, cognitive
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis - Differential ... papules and Gottron sign ... ) • Shawl sign ... Polymyositis or ALS ... : • PBC, autoimmune
Evaluation of Recurrent Falls Core Concept: Maintaining an upright posture requires the integrated function of multiple systems. Disruption in
presyncope, exertional symptoms ... positive Romberg sign ... (ALS) • Clues: ... Falls #Diagnosis #Differential ... #Evaluation #Geriatrics
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