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Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
Thrombocytopenia (HIT) - Diagnosis ... heparin-PF4 complex → plt ... hypercoagulable state and plt ... : • Clinical Suspicion ... non-heparin A/C if clinical
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... for decreased PLT ... for decreased PLT ... #Differential #Diagnosis
Dermatomes of the Upper and Lower Limbs (Modified, after Keegan, J. J., and Garrett, F. D.)

According
According to the clinical ... to detect and plot ... #Diagnosis #Anatomy
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
organ damage Clinical ... abnormalities - PLT ... Cryoprecipitate - PLT ... #Coagulation #diagnosis
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Cr, ↓Glucose, ↓PLT ... ) Differential Diagnosis ... Maternal Support - Critical ... obstetrics #obgyn #diagnosis
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Auto-amplification loop Diagnosis ... accumulation of clinical ... Assessment • Clinical ... Cytopenia +++ (Plt ... Lymphohistiocytosis #diagnosis
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Leukocyte count ↑ PLT ... Significant ↓ PLT ... count • ↓Hg & PLT ... Hematology #Oncology #Diagnosis
Critical and Emergent Causes of Neuromuscular Weakness
CRITICAL DIAGNOSES 
 - Cerebral cortex or subcortical 
 -
Critical and Emergent ... Neuromuscular Weakness CRITICAL ... DIAGNOSES - ... Muscle EMERGENT DIAGNOSES ... Neurology #Causes #Diagnosis
Urethral Injury in the Emergency Department

Clinical Features, Diagnostics and Treatment

#Urology #Diagnosis #Management #Urethral #Injury #Urethrogram
Emergency Department Clinical ... Features, Diagnostics ... Treatment #Urology #Diagnosis
Chest Pain Differential Diagnosis and Clinical Features

#Diagnosis #ChestPain #Differential #Features #Comparison #Table
Pain Differential Diagnosis ... and Clinical Features ... #Diagnosis #ChestPain