17 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... for decreased PLT ... changes), high MCV anemia ... Diagnosis #Causes #Workup ... #hematology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
Diagnosis and Management ... ♀, ↑Age, ESRD Pathophysiology ... heparin-PF4 complex → plt ... hypercoagulable state and plt ... #Treatment #Hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Schistocytes, thrombocytopenia ... ARUPLabs #Hemolytic #Anemia ... Diagnosis #Algorithm #workup ... #hematology #testing
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... abnormalities - PLT ... Cryoprecipitate - PLT ... causes #treatment #management ... #hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia ... infections/fevers • Thrombocytopenia ... • ↓ WBC • ↓ PLT ... #oncology #hematology ... #diagnosis #management
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
5) Symptoms of anemia ... or thrombocytopenia ... marrow failure with anemia ... or thrombocytopenia ... hemeonc #diagnosis #management
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... Cr, ↓Glucose, ↓PLT ... Liver #Pregnancy #hepatology ... obgyn #diagnosis #management ... #pathophysiology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
for Thrombotic Thrombocytopenic ... result in severe anemia ... immune hemolytic anemia ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup ... #Hematology
Scurvy (Vitamin C Deficiency) - Diagnosis and Management

Vitamin C is required for hydroxylation of proline residues
Diagnosis and Management ... breath, wasting, anemia ... Loss of teeth Anemia ... cutaneous vasculitis, thrombocytopenia ... #AscorbicAcid #Pathophysiology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Significant ↓ PLT ... - infiltrates (anemia ... , thrombocytopenia ... count • ↓Hg & PLT ... #Leukemia #Hematology