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table toxidromes hematology anticholinergics differential hyperthermic opioids sympathomimetics anemia aplastic dermatology differentiate hyperthermia hypnotics leukemia management monoclonal neurolepticmalignant nms paraproteinemias
Hyperthermic Syndromes - This table summarizes the similarities and differences between some toxicologic causes of hyperthermic
Hyperthermic Syndromes ... differences between some toxicologic ... • Serotonin syndrome ... #Comparison #Table ... #Diagnosis #Toxicology
Signs and Symptoms of Toxidromes Sympathomimetic / GABAergic withdrawal Cholinergic Anticholinergic Opioid withdrawal Neuroleptic malignant syndrome Serotonin
Neuroleptic malignant syndrome ... Serotonin syndrome ... #Toxidromes #Comparison ... Sympathomimetics #Diagnosis ... #Toxicology
Serotonin Syndrome - THINK: FAST - FAST onset - FAST movements (agitation, akathisia, HYPERreflexia) - FAST
Serotonin Syndrome ... Neuroleptic Malignant Syndrome ... NeurolepticMalignant #Syndrome ... #Diagnosis #Toxicology ... #Comparison #Differentiate
Toxidromes Summary Table Heart Rate - Respiratory Rate - Blood Pressure - Mental Status - Skin -
• Serotonin Syndrome ... #Toxidromes #comparison ... #table #toxicology ... #diagnosis
A toxidrome is a syndrome (set of symptoms) caused by specific medications or toxins. There are 5
toxidrome is a syndrome ... antihistamines #Diagnosis ... #Toxicology #Toxidromes ... #Comparison #Table
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Sweet Syndrome ... onset of tender or painful ... Leukemia cutis Diagnosis ... #diagnosis #dermatology ... #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Constitutional Syndromes ... • ↓ WBC • ↓ PLT ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
capillary leak syndrome ... Hyperviscosity syndrome ... Organomegaly+↑RBC/plt ... #Differential #Diagnosis ... #Oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
develop leukostasis syndrome ... count • ↓Hg & PLT ... • Tumor lysis syndrome ... Leukemia #Hematology #Oncology ... #Diagnosis
Hyperthermic Toxidromes Five toxidromes may present with overlapping features: hyperthermia, rhabdomyolysis, altered mental status/seizures. • Sympathomimetic -
• Serotonin Syndrome ... Hyperthermic #Toxidromes #comparison ... #table #diagnosis ... #differential #toxicology
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