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hematology diagnosis management algorithm anticoagulation cancer malignancy vte anemia aplastic chemotherapy cryofibrinogenemia cyp3a4 dermatologic differential gpa granulomatosis hemeonc heparin hit
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis. Currently, edoxaban and rivaroxaban are the only
anticoagulants (DOACs ... filtration rate; DOAC ... #DOAC #VTE #Malignancy ... Anticoagulation #Management #Hematology ... #Oncology
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 (DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓) of cytochrome p450 CYP3A4 and P-glycoprotein. DOACs are substrates
(DOAC interactions ... DOACs are substrates ... metabolization of DOACs ... #Chemotherapy #Oncology ... #Hematology #Interactions
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Dermatologic Manifestations ... purpura (16%) • Painful ... #Dermatologic ... Polyangiitis #GPA #dermatology ... rash #diagnosis #rheumatology
Treatment algorithm for VTE in Malignancy (A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
DOAC, direct oral ... #DOAC #VTE #Malignancy ... Anticoagulation #Management #Hematology ... #Oncology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook Presentation: • Plts ↓50% (nadir
heparin-PF4 complex → plt ... hypercoagulable state and plt ... , Bivalirudin, DOAC ... Management #Treatment #Hematology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Organomegaly+↑RBC/plt ... Autoimmunity: • -MM/WM: Vasculitis ... Hypergammaglobulinemic macular Vasculitis ... Paraproteinemias #Hematology ... Differential #Diagnosis #Oncology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
malignancies, vasculitis ... sensitivity • Painful ... reticularis • Painful ... Cryofibrinogenemia #diagnosis #rheumatology ... #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Leukocyte count ↑ PLT ... Significant ↓ PLT ... count • ↓Hg & PLT ... #Leukemia #Hematology ... #Oncology #Diagnosis
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
onset of tender or painful ... Leukocytoclastic vasculitis ... Syndrome #diagnosis #dermatology ... #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
• ↓ WBC • ↓ PLT ... Aplastic #Anemia #oncology ... #hematology #diagnosis
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