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diagnosis classification cryoglobulinemia cryoglobulins differential erythematosus icl idiopathic lupus lymphocytopenia lymphopenia management sle systemic types vasculitis
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... Hypocomplementemia • Can cause ... /aggregate) of CD4 ... Nephrogenic DI Hematologic ... #Syndrome #Rheumatology
Idiopathic CD4 Lymphopenia (ICL) / Lymphocytopenia DIAGNOSTIC CRITERIA FOR ICL • Persistent CD4 T-cell lymphopenia •
• Autoimmune ... (Sjogren, SLE, Kikuchi ... chemotherapy) • Genetic syndromes ... ICL #diagnosis #hematology ... #Differential #Causes
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... infection • Autoimmune ... • Low serum C4 ... classification #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
dermatomyositis, Sjogren ... disease • Non-autoimmune ... rheumatologic diseases ... • May involve PNS ... Erythematosus #Diagnosis #Rheumatology
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