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Common Etiologies of Cirrhosis

Inflammation

 - Hepatitis B (15 percent)

 - Hepatitis C (47 percent)

 - Schistosomiasis
Nonalcoholic fatty liver ... disease (Budd-Chiari syndrome ... #Diagnosis #Differential ... #Hepatology #Cirrhosis ... #Causes
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... Volume (MCV) - Differential ... Myelodysplastic Syndromes ... #elevatedMCV #Differential ... #Hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Causes of Anemia ... Volume (MCV) - Differential ... Renal Disease, Liver ... Reticulocytosis • Liver ... #Hematology
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
Hypertension - Differential ... >10 mmHg - clinically ... and hepatorenal syndrome ... Clues to non-cirrhotic ... #hepatology
Ascites - Differential Diagnosis
Chronic liver disease (cirrhosis or chronic hepatitis) - 80%
Underlying malignancy - 10%
Congestive heart
Ascites - Differential ... Diagnosis Chronic liver ... disease (cirrhosis ... Fitz-Hugh-Curtis syndrome ... #Diagnosis #hepatology
Causes of Portal Hypertension According to Site of Vascular Obstruction
1) Prehepatic pre-sinusoidal: Portal vein thrombosis due
Causes of Portal ... , Polycystic liver ... post-sinusoidal: Budd-Chiari syndrome ... portalhypertension #phtn #differential ... #hepatology
Dyspnea - Differential Diagnosis Framework

Cardiovascular Causes of Dyspnea:
 • Myocardium:
	- Heart failure
	- CAD/ACS
	- Valvulopathy
 • Electrical:
	-
Dyspnea - Differential ... - Water - Pus ... Hepatopulmonary syndrome ... Transverse myelitis • Hematology ... : - Anemia
Hepatomegaly - Differential Diagnosis Algorithm
Malignant
 • Primary Carcinoma
 • Metastases
 • Lymphoma
 • Leukemia
 • Polycythemia
Non-Malignant • Fatty Liver ... • Budd-Chiari Syndrome ... Primary Biliary Cirrhosis ... Diagnosis #Algorithm #Causes ... #Hepatology
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
, Liver diseases ... Myelodysplastic syndrome ... Hemolytic uremic syndrome ... key #diagnosis #differential ... #hematology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
- Differential ... PK, HbC, HbSS, PNH ... Non-megaloblastic: Liver ... MCV #Algorithm #Differential ... #Diagnosis #hematology