15 results
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... common sites: hip, shoulder ... Osteomyelitis / Septic Arthritis ... • Differentiate ... #hematology
Gout (Gouty Arthritis) - MSK Radiology
Imaging Findings:
 • Eccentric soft-tissue densities surrounding the third proximal interphalangeal
mass and NO prior signs ... • This case should ... Differential diagnosis ... • PVNS/Giant Cell ... #rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
- Arthritis Differential ... axial (spine, shoulders ... noninflammatory Signs ... Joint #pain #Differential ... #Diagnosis #MSK
Dermatological semiology of Cutaneous Vasculitis 

Clinicopathologic correlations
 • Purpura, papules, pustules, necrosis: involvement of small vessels
Identification of causes ... Vasculitis #dermpath #dermatology ... #semiology #signs ... lesions #diagnosis #clinical ... pathology #lesions #differential
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... Behcet syndrome (Clinical ... Behcet disease) Differential ... Nonsurgical abdominal pain ... diagnosis #management #signs
13 Dangerous Causes of Headache:
 - subarachnoid hemorrhage: family history, PCKD, known berry aneurysm, sudden and
13 Dangerous Causes ... temporal (giant cell) arteritis ... claudication, shoulder ... dissection: unilateral pain ... thrombophilia, neurologic signs
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Rarely dominate the clinical ... burning sensation or pain ... • Giant cell arteritis ... Polyangiitis #GPA #dermatology
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
, and back and shoulders ... (in a shawl sign ... auricular papules Clinical ... • Arthralgia/arthritis ... #dermatology #diagnosis
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
blisters containing pus ... Clinical Features ... nonerosive inflammatory arthritis ... Rule out other causes ... diagnosis #management #Dermatology
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Diagnosis = clinical ... systemic sx + signs ... very remarkable w/differential ... claudication: pain ... chews, not just pain