19 results
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... • Chronic lung ... lymphocytic interstitial lung ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology
Bilateral B-Lines in case of Pneumonia on Lung POCUS

Young healthy pt with fever/dyspnea. POCUS lung exam
POCUS lung exam ... sliding: Pulmonary ... interstitial diffuse infections ... Lung POCUS shows ... #POCUS #clinical
Hemoptysis - Differential Diagnosis Framework
Massive Hemoptysis: >150-300 mL in 24h
Airway disease: 
 • Bronchitis, Bronchiectasis, Malignancy
Parenchyma: • Infection ... TB, Necrotizing PNA ... Kaposi's sarcoma • Rheumatologic ... Differential #Diagnosis #pulmonary ... #causes
Clinical Classification of Pulmonary Hypertension

1. Pulmonary arterial hypertension from pulmonary vasculopathy
Idiopathic pulmonary arterial hypertension
Heritable gene mutations
Clinical Classification ... diseases - HIV infection ... Interstitial lung ... multifactorial mechanisms Hematologic ... #Differential #Causes
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
status NTM Cause ... Illnesses: • Pulmonary ... Hematologic malignancy ... Disease: Clinical ... Disease: • Clinical
COVID19 vs CHF on POCUS

Spot the difference. 2 pts presenting with nearly same symptoms. Left COVID
COVID19 vs CHF on POCUS ... difference. 2 pts ... Left COVID pneumonia ... lines due to other causes ... #Clinical #Lung
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Malignancy • Infections ... thrombophlebitis, pulmonary ... cryoglobulins • Negative causes ... Cryofibrinogenemia #diagnosis #rheumatology ... #hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
nervous system (CNS ... rash) • Heart, lung ... SLE], AOSD) • Infection ... Diagnosis #Management #Hematology ... #Rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Non-autoimmune rheumatologic ... fibromyalgia) • Infections ... • May involve PNS ... Erythematosus #Diagnosis #Rheumatology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... salivary ducts Clinical ... Nephrogenic DI Hematologic ... MALT Lymphoma • Lung ... Sjogrens #Syndrome #Rheumatology