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diagnosis management rheumatology syndrome dermatology activation alkaline alp anemia antinxp2 antinxp2dm aplastic cerebritis cns dermatomyositis differential disorders eosinophil eosinophils erythematosus
Hypereosinophilia and Hypereosinophilic Syndrome • Secondary Hypereosinophilic Syndrome • Clinically Relevant HES Variants • When to
Syndrome • Secondary ... Hypereosinophilic Syndrome • Clinically ... Diagnosis and Treatment ... Algorithm Matthew ... #eosinophilia #
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Testing Algorithm ... • Screen for secondary ... causes of eosinophilia ... glucocorticoid treatment ... Differential #diagnosis #hematology
Secondary Syphilis Rash Secondary syphilis is the most contagious of all the stages of this disease, and
Rash Secondary ... , but without treatment ... resembling rashes caused ... #Clinical #Photo ... #Dermatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... autoantibodies that will cause ... Puncture, EEG Treatment ... APS), Secondary ... #neurology #rheumatology
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
Phosphatase Of Clinical ... pain • loss of secondary ... membrane into the CNS ... Waddling gait - Difficulty ... Phosphatase: • Other causes
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Classified among the secondary ... Fever is the main clinical ... nervous system (CNS ... Petechial or purpuric rash ... Treatment: • Corticosteroids
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia Clinical ... skin color • Difficulty ... and petechiae Causes ... - Hepatitis, eosinophilic ... aplastic anemia Treatment
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
other diseases • Secondary ... Hypocomplementemia • Can cause ... salivary ducts Clinical ... Nephrogenic DI Hematologic ... Adenocarcinoma Treatment
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
subcutaneous edema Pts ... (blue-purple) rash ... auricular papules Clinical ... Muscle atrophy may cause ... positive patients Treatment
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