9 results
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Kasabach-Merritt syndrome ... deficiencies - PNH ... Gardner-Diamond syndrome ... Differential #Diagnosis #hematology ... #nonpalpable #dermatology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
• Nephrotic Syndrome ... coagulation and other causes ... of purpura fulminans ... - COVID-19 - PNH ... pathophysiology #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... ) - HELLP syndrome ... thrombocytopenic purpura ... hemoglobinuria (PNH ... differential #diagnosis #hematology
Adie's Pupil on Physical Exam

Adie's pupil is a neurological disorder characterized by a tonically dilated pupil
by a viral or bacterial ... #Adies #Pupil #PhysicalExam ... #clinical #video ... ophthalmology #neurology ... #syndrome
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Henoch Schonlein Purpura ... Non-Palpable Rash: - Purpura ... blood test • Serology ... #dermatology #physicalexam
Nikolsky's Sign in Toxic Epidermal Necrolysis (TEN)

Nikolsky's sign is a clinical dermatological sign which is present
Stevens-Johnson Syndrome ... , caused by the ... Nikolskys #Sign #TEN #Dermatology ... #PhysicalExam # ... Video #Clinical
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
affects the skin, neurologic ... • Coronary arteries ... cognitive impairment, neurologic ... tract, and often causes ... Thrombosis and arterial
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
lesions, palpable purpura ... skin injury) • Neurologic ... basal ganglia, CNS ... Vascular Disease: Arterial ... signs #symptoms #rheumatology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Skin necrosis • Purpura ... cryoglobulins • Negative causes ... to medium-sized arteries ... Antiphospholipid syndrome ... #hematology