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diagnosis differential management algorithm alkaline alp anemia antinxp2 antinxp2dm aplastic clinical gottronspapules heliotrope hepatology hyophosphatasia leukemia low monoclonal paraproteinemias petechiae
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
et diutinum Neurologic ... Scleromyxedema (CNS ... Amyloidosis (CVS+PNS ... Paraproteinemias #Hematology ... Differential #Diagnosis #Oncology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Causes: - Idiopathic ... , breast CA - Hematologic ... multiforme - Dermatomyositis ... Syndrome #diagnosis #dermatology ... #oncology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... blood test • Serology ... Diagnosis #Algorithm #Causes ... #dermatology #physicalexam
Dermatomyositis with heliotrope rash, shawl sign, and Gottron's papules A middle-aged man describes progressive difficulty combing his
Dermatomyositis ... describes progressive difficulty ... out this is a case ... of dermatomyositis ... GottronsPapules #dermatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
involvement • 30%: CNS ... -> AML: Blast crises ... count ↑ PLT • ↑ PBS ... #Leukemia #Hematology ... #Oncology #Diagnosis
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
skin color • Difficulty ... and petechiae Causes ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
membrane into the CNS ... respiratory failure • Neurologic ... Waddling gait - Difficulty ... Phosphatase: • Other causes ... Hyophosphatasia #hepatology
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
Anti-NXP-2 Dermatomyositis ... subcutaneous edema Pts ... Muscle atrophy may cause ... diagnosis #management #rheumatology ... #dermatology
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