9 results
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Low Alkaline Phosphatase ... Of Clinical Importance ... membrane into the CNS ... Waddling gait - Difficulty ... : • Other causes
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Prolonged PT/PTT • Low ... organ damage Clinical ... involvement (2%) Cutaneous ... Treat primary cause ... treatment #management #hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... anti-Smith Ab, low ... permanent alopecia Differential ... • May involve PNS ... , lymphopenia, low
Cutaneous Mucormycosis Eschar
30 M HIV cd4 10 VL 30k traumatic injury of arm few months ago
immunosuppressed pts ... failure, infant low ... Mucormycosis #Eschar #dermatology ... #skin #clinical ... #photo
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
originate from a low-grade ... Viral Infection Clinical ... presentation) • Cutaneous ... ) Differential ... hemolytic #anemia #hematology
Gout (Gouty Arthritis) - MSK Radiology
Imaging Findings:
 • Eccentric soft-tissue densities surrounding the third proximal interphalangeal
commonly intermediate-low ... Case description ... Differential diagnosis ... • PVNS/Giant Cell ... diagnosis #msk #rheumatology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
• AIDS with low ... noncompliance • Clinical ... initiation Clinical ... Leishmaniasis Differential ... Inflammatory #Syndrome #Differential
Polymyalgia Rheumatica (PMR) Diagnosis and Management Summary

WHAT?
 • Polymyalgia rheumatica (PMR) is a common systemic inflammatory
disease of unknown cause ... commonly describe difficulty ... symptoms may include low-grade ... CLINICAL: • Physical ... normal and can help differentiate
Anti-NXP-2 Dermatomyositis

What?
DM with generalized subcutaneous edema
Pts have more myalgias, more severe weakness, and an increased prevalence
subcutaneous edema Pts ... How? ... in the neck Cutaneous ... auricular papules Clinical ... Muscle atrophy may cause