14 results
Dyspnea - Differential Diagnosis Framework

Cardiovascular Causes of Dyspnea:
 • Myocardium:
	- Heart failure
	- CAD/ACS
	- Valvulopathy
 • Electrical:
	-
Cardiovascular Causes ... - Water - Pus ... syndrome Other Causes ... Transverse myelitis • Hematology ... : - Anemia
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
• Secondary Causes ... - Hemolytic anemia ... deficiencies - PNH ... Differential #Diagnosis #hematology ... #rheumatology #
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
 -
Causes of Extravascular ... • PCH • PNH ... immune-complex hemolytic anemia ... Diagnosis #Algorithm #Causes ... #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... hemoglobinuria (PNH ... Extravascular #Causes ... differential #diagnosis #hematology ... #anemia
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... skin color • Difficulty ... and petechiae Causes ... #oncology #hematology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
membrane into the CNS ... • Pernicious anemia ... Waddling gait - Difficulty ... Phosphatase: • Other causes ... Hyophosphatasia #hepatology
Dermatomyositis with heliotrope rash, shawl sign, and Gottron's papules

A middle-aged man describes progressive difficulty combing his
Dermatomyositis ... describes progressive difficulty ... out this is a case ... GottronsPapules #dermatology ... #clinical #photo
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
involvement • 30%: CNS ... -> AML: Blast crises ... count ↑ PLT • ↑ PBS ... - infiltrates (anemia ... #Leukemia #Hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Still disease, dermatomyositis ... Non-autoimmune rheumatologic ... • May involve PNS ... lymphopenia, low PLT • Anemia ... Erythematosus #Diagnosis #Rheumatology
Capnocytophaga Canimorsus Skin Rash

40 M presents w/ N, V, severe epigastric pain. SHx: smoker, drinks 18
Bandemia, AKI. ... dogs & latter can cause ... gram-negative bacillus cause ... the organism is difficult ... #clinical #photo