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diagnosis differential algorithm lad localized lymphadenopathy management monoclonal anemia antinxp2 antinxp2dm aplastic dermatomyositis diffuse gammopathies leukemia multiplemyeloma paraproteinemias petechiae petechial
Causes of Diffuse and Localized Lymphadenopathy - Differential Diagnosis Algorithm • Reactive (Inflammatory / Infectious) •
Causes of Diffuse ... ) #Diffuse #Focal ... Diagnosis #Algorithm #Causes ... #Hematology #Oncology
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
ratio ≥100 • >1 focal ... Causes of false- ... #Gammopathies #MGUS ... #diagnosis #hematology ... #oncology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• MM • WM • MGUS ... Scleromyxedema (CNS ... Amyloidosis (CVS+PNS ... Paraproteinemias #Hematology ... Differential #Diagnosis #Oncology
Causes of Localized Lymphadenopathy - Differential Diagnosis Algorithm Cervical: - Anterior • Infection
Causes of Localized ... #Localized #Focal ... Diagnosis #Algorithm #Causes ... #Hematology #Oncology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Rash - Differential ... Urinalysis • Fecal ... Diagnosis #Algorithm #Causes ... #dermatology #physicalexam
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
involvement • 30%: CNS ... -> AML: Blast crises ... count ↑ PLT • ↑ PBS ... #Leukemia #Hematology ... #Oncology #Diagnosis
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
skin color • Difficulty ... and petechiae Causes ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
subcutaneous edema Pts ... (blue-purple) rash ... Muscle atrophy may cause ... diagnosis #management #rheumatology ... #dermatology
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