14 results
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Phosphatase Of Clinical ... membrane into the CNS ... mineralization Symptoms ... respiratory failure • Neurologic ... Waddling gait - Difficulty
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
) Clinical Manifestations ... Demyelinating Syndrome, Headache ... autoantibodies that will cause ... #CNS #neurology ... #rheumatology #
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
HIV / AIDS - Differential ... should be based on clinical ... : Fever, headache ... Demyelinating disease caused ... #Infections #differential
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
injury) • Neurologic ... symptoms (headache ... Behcet disease) Differential ... Oral aphthae : SLE ... #rheumatology #
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework

Heat Cramps:
 • Muscle pain or spasm -
Heat Stroke - Differential ... blisters on the skin ... Syncope • Signs/Symptoms ... - Athlete - difficulty ... #diagnosis #causes
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
rapid onset of symptoms ... -> AML: Blast crises ... Blast Phase: • Headaches ... CLL -> Invade Skin ... #Leukemia #Hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... 3rd Decade Skin ... permanent alopecia Differential ... and CNSHeadache ... Induced Lupus: • Symptoms
CNS Infections - Viral Encephalitis and Bacterial Meningitis - Differential Diagnosis Framework

Viral Encephalitis:
MCC: Enteroviruses (e.g., coxsackievirus
CNS Infections - ... Coltivirus Symptoms ... • Common clinical ... influenzae Symptoms ... #diagnosis #neurology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
diseases, such as SLE ... 50 years • New headache ... , neurologic, and ... of headache, cognitive ... tract, and often causes
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia Clinical ... Irritability • Headaches ... • Pale skin color ... • Difficulty breathing ... and petechiae Causes