13 results
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... Early dz difficult ... Osteomyelitis / Septic Arthritis ... • Differentiate ... #hematology
Causes of Polycythemia (Erythrocytosis) - Differential Diagnosis Algorithm
Relative - Normal RBC Mass / Decreased Plasma Volume
Causes of Polycythemia ... Erythrocytosis) - Differential ... Splenomegaly, Increased PMNs ... Family History, early ... #Hematology
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
the afternoon or early ... #Joint #Pain #MSK ... #rheumatology # ... approach #workup ... #differential #
Gout (Gouty Arthritis) - MSK Radiology
Imaging Findings:
 • Eccentric soft-tissue densities surrounding the third proximal interphalangeal
Gout (Gouty Arthritis ... ) - MSK Radiology ... Differential diagnosis ... • PVNS/Giant Cell ... #rheumatology
Ascites - Diagnostic Approach and Differential Diagnosis
The most common causes: cirrhosis, malignancy and heart failure. Approx
The most common causes ... more than one cause ... ) / absence of edema ... Jcortesizaguirr #Ascites #workup ... Diagnosis #hepatology
13 Dangerous Causes of Headache:
 - subarachnoid hemorrhage: family history, PCKD, known berry aneurysm, sudden and
13 Dangerous Causes ... at home or at work ... distribution, eyelid edema ... Fatal #Dangerous #Deadly ... #Differential
Polycythemia - Differential Diagnosis Algorithm
Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Polycythemia - Differential ... an underlying cause ... Better call hematology ... JAK2 V617F) and MPNs ... #hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Skin Disease Classification ... permanent alopecia Differential ... lower extremity edema ... proteinuria, dependent edema ... • May involve PNS
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
Like in this case ... #Joint #Pain #MSK ... #rheumatology # ... approach #workup ... #differential #
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
intralobular bile ducts causes ... Bilirubin - Normal early ... bile ducts Differential ... cholangitis #diagnosis #workup ... #hepatology