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diagnosis differential management product transfusion anemia comparison dyspnea extravascular hemolysis hemolytic intravascular leukemia mds myelodysplasia myelodysplastic pulmonary sob syndromes table
Dyspnea - Differential Diagnosis Framework Cardiovascular Causes of Dyspnea: • Myocardium: - Heart failure - CAD/ACS - Valvulopathy • Electrical: -
Cardiovascular Causes ... Heart failure - CAD ... - Water - Pus ... - Blood • Pleura ... Transverse myelitis • Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... hemoglobinuria (PNH ... disease, Copper and lead ... Extravascular #Causes ... differential #diagnosis #hematology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
FNHTR once had ... Causes purpura & ... TRALI): Leading cause ... more likely to cause ... diagnosis #management #hematology
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
- Transfusion Reactions ... of high parity blood ... without other cause ... with pulmonary edema ... #hematology #diagnosis
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
FNHTR once had ... Causes purpura & ... TRALI): Leading cause ... more likely to cause ... diagnosis #management #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
the peripheral blood ... activity • ↓ LAP ... -> AML: Blast crises ... #Leukemia #Hematology ... #Oncology #Diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... skin that are caused ... compounds, alcohol, lead ... Syndromes #diagnosis #hematology ... #oncology
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