PNS hematology causes edema hepatology gastroenterology oncology lad reactions classification

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Differential Diagnosis for Hemolytic Anemia
Intrinsic Causes:
• Enzyme deficiencies ex. G6PD, pyruvate kinase
• Hemoglobinopathies

Anemia Intrinsic Causes ... Other agents ex. lead ... • Transfusion reactions ... #classification ... #hematology

Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
• Mechanical Trauma (Microangiopathic hemolytic anemia):

Extravascular Causes ... hemoglobinuria (PNH ... disease, Copper and lead ... Extravascular #Causes ... differential #diagnosis #hematology

Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear

activity • ↓ LAP ... -> AML: Blast crises ... count ↑ PLT • ↑ PBS ... #Leukemia #Hematology ... #Oncology #Diagnosis

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