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diagnosis algorithm rheumatology sle anemia antinxp2 antinxp2dm cardiology chf clinical criticalcare dermatomyositis dress erythematosus extravascular foamed hcq heartfailure hemolysis hemolytic
Causes of Isolated Neutropenia - Differential Diagnosis Algorithm Congenital Medications • Anticonvulsants • Antibiotics • Antithyroid • Antihypertensive
Causes of Isolated ... Neutropenia - Differential ... Algorithm Congenital Medications ... Destruction • Systemic Lupus ... #Hematology
Hydroxychloroquine Serum Measurement in SLE • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
200ng/mL Best indications ... • Special cases ... Measurement #SLE #rheumatology ... #pharmacology # ... levels #lupus #management
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... hemoglobinuria (PNH ... usually IgG) (e.g. lupus ... #differential # ... diagnosis #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Malignancy (e.g. hematologic ... lower extremity edema ... • May involve PNS ... activation and/or medications
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Rash - Differential ... Immunosuppressed • New medication ... Autoimmune Vasculitis (lupus ... #dermatology #physicalexam
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
• Facial Edema ... in 70% of cases ... Resolution > 15 days Differentials ... DRESS #Syndrome #dermatology ... #diagnosis #management
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
JVD, Orthopnea/PND ... the determined cause ... #diagnosis #differential ... #algorithm #management ... icu #clinical #pharmacology
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
generalized subcutaneous edema ... Pts have more ... Muscle atrophy may cause ... Dermatomyositis #diagnosis #management ... dermatology
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