29 results
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
Secondary ... • Clinically ... suspect underlying hematologic ... and Treatment Algorithm ... #HES #Hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
leakage of RBC's secondary ... Kasabach-Merritt syndrome ... deficiencies - PNH ... Differential #Diagnosis #hematology ... #nonpalpable #dermatology
Recurrent / Breakthrough DVT During Anticoagulation

Subtherapeutic Anticoagulation
Hypercoagulable State 
 - Antithrombin deficiency 
 - Hypercoagulability ot
APLS - MPN/PNH ... Structural - Pelvic masses ... - May-Thurner syndrome ... anticoagulation #hematology ... #differential #algorithm
Genital Lesions - Differential Diagnosis Algorithm
Elevated - Vesicles:
 • Herpes simplex
Elevated - Papules / Plaques -
Differential Diagnosis Algorithm ... acuminata) • Secondary ... ) • Reiter's syndrome ... #skinlesions #dermatology ... #causes
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Systemic and Primary Causes ... Myelodisplastic syndrome ... Pruritus #primary #secondary ... #generalized #dermatology ... #causes
Approach to Elevated Tryptase - Differential Diagnosis Framework

The DDx of elevated tryptase can be broken down
pass = Dangerous secondary ... • Mast cell activation ... syndrome • Mastocytosis ... • Other hematologic ... Differential #Diagnosis #hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation ... Classified among the secondary ... Clinical Presentation ... nervous system (CNS ... #Management #Hematology
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Nail Disorders secondary ... • Nephrotic syndrome ... #dermatology #Differential ... #Diagnosis #Algorithm ... #causes
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
sequestration and activation ... without other cause ... with pulmonary edema ... Transfusion #Reactions #hematology ... diagnosis #comparison #table
Eczematous Skin Rash - Differential Diagnosis Algorithm
Eczematous - Pruritic/Scaly/Erythematous lesions. Usually poorly demarcated
 • Atopic Dermatitis
Differential Diagnosis Algorithm ... Secondary to venous ... pigmentation, edema ... Eczematous #SkinRash #dermatology ... #causes