21 results
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... purple, hemorrhagic skin ... leakage of RBC's secondary ... #hematology #rheumatology ... #nonpalpable #dermatology
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
decades of life Causes ... and clinical associations ... #Urticaria #diagnosis ... #rheumatology # ... comparison #table
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
AIHA Primary Secondary ... lymphoproliferative disorder Secondary ... Viral Infection Clinical ... disease (younger pts ... hemolytic #anemia #hematology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Cryofibrinogenemia Clinical ... Cryofibrinogenemia Diagnosis ... : • + Clinical ... cryoglobulins • Negative causes ... hematology
Eczematous Skin Rash - Differential Diagnosis Algorithm
Eczematous - Pruritic/Scaly/Erythematous lesions. Usually poorly demarcated
 • Atopic Dermatitis
Eczematous Skin ... Secondary to venous ... pigmentation, edema ... Eczematous #SkinRash #dermatology ... #Algorithm #causes
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Amyloidosis (CVS+PNS ... anemia due to cold ... Paraproteinemias #Hematology ... #Differential #Diagnosis ... #Oncology
Secondary Syphilis Rash
Secondary syphilis is the most contagious of all the stages of this disease, and
Skin rash and malaise ... resembling rashes caused ... #Rash #Diagnosis ... #Clinical #Photo ... #Dermatology
Primary Dermatological Lesions
Primary lesions are physical changes in the skin considered to be caused directly by
considered to be caused ... associated with secondary ... area of dermal oedema ... nettle sting #Diagnosis ... #Dermatology #Skin
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
blue-purple) rash with edema ... ulcerations • Skin ... auricular papules Clinical ... • Skin vasculopathies ... #dermatology #diagnosis
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... bone marrow and secondary ... CLL -> Invade Skin ... #Leukemia #Hematology ... #Oncology #Diagnosis