16 results
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear

Visual or auditory symptoms in conjunction
nervous system (CNS ... and less common diseases ... Inflammatory causes ... polychondritis • Behcet ... #neurology #inflammatory
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent
Multiple Ring-Enhancing Lesions:
 • Toxoplasmosis (CD4 < 100)
 • Other
CNS Ring-Enhancing ... + toxo IgG • CNS ... 30% present w/ CNS ... Inflammatory: ... @AnnKumfer #CNS
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
(25-75%): Inflammatory ... basal ganglia, CNS ... meningitis), MCC CNS ... collaboration • CNS ... #management #signs
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Demyelinating Syndrome ... Cerebrovascular Disease ... Treatment: • Inflammatory ... Erythematosus #SLE #CNS
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
background of a highly inflammatory ... release of pro-inflammatory ... nervous system (CNS ... #Diagnosis #Management ... #Hematology #Rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
photosensitivity, inflammatory ... lower extremity edema ... proteinuria, dependent edema ... • May involve PNS ... and CNS • Headache
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Parotid swelling CNS ... nervous system (CNS ... • 8%-27% for CNS ... Nephrogenic DI Hematologic ... Diagnosis #Management
Hypertrophic Pachymeningitis - Differential Diagnosis Framework

Pachymeningitis is a rare condition that causes areas of a layer
Neurosyphilis • CNS ... pachymeningitis • CNS ... meningitis Inflammatory ... polychondritis • Behçet ... brain sagging syndrome
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... involvement • 30%: CNS ... : CNS manifestations ... #Leukemia #Hematology ... #Oncology #Diagnosis
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
a rare chronic inflammatory ... blisters containing pus ... Rule out other causes ... osteoarticular and skin disease ... diagnosis #management