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rheumatology differential dermatology management arterial autoimmune clinical cryofibrinogenemia embolism leukemia myopathy myositis nikolskys nonpalpable oncology palpable pathophysiology purpura sapho sign
Nikolsky's Sign in Toxic Epidermal Necrolysis (TEN) Nikolsky's sign is a clinical dermatological sign which is present
Stevens-Johnson Syndrome ... syndrome, caused ... differentiating between the diagnosis ... #PhysicalExam # ... Video #Clinical
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 Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... purple, hemorrhagic skin ... Kasabach-Merritt syndrome ... deficiencies - PNH ... #hematology #rheumatology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
blisters containing pus ... • A clinical diagnosis ... Rule out other causes ... diagnosis #management ... #Dermatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Lacrimal swelling • Skin ... Diagnosis: • Dry ... Hypocomplementemia • Can cause ... Nephrogenic DI Hematologic ... Cryoglobulinemia (4%-12%), Raynaud
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
- Differential Diagnosis ... Testosterone - Coumadin skin ... • Nephrotic Syndrome ... pathophysiology #hematology ... #differential #diagnosis
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Arthralgias • Raynaud ... Cryofibrinogenemia Diagnosis ... cryoglobulins • Negative causes ... Antiphospholipid syndrome ... hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... • Tumor lysis syndrome ... CLL -> Invade Skin ... #Leukemia #Hematology ... #Oncology #Diagnosis
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
- Differential Diagnosis ... Vasculitis Differential Diagnosis ... tract, and often causes ... #Differential #Diagnosis ... #Rheumatology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
) • Anti-Mi2 (skin ... joint pain and Raynaud ... aspiration > 50% of pts ... • Myositis • Raynaud ... statins - probably caused
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