6 results
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
Testosterone - Coumadin skin ... • Nephrotic Syndrome ... coagulation and other causes ... - COVID-19 - PNH ... pathophysiology #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
purple, hemorrhagic skin ... Kasabach-Merritt syndrome ... deficiencies - PNH ... Gardner-Diamond syndrome ... Differential #Diagnosis #hematology
Nikolsky's Sign in Toxic Epidermal Necrolysis (TEN)

Nikolsky's sign is a clinical dermatological sign which is present
Stevens-Johnson Syndrome ... syndrome, caused ... Nikolskys #Sign #TEN #Dermatology ... #PhysicalExam # ... Video #Clinical
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Arthralgias • Raynaud ... cryoglobulins • Negative causes ... Antiphospholipid syndrome ... DIC • Septic emboli ... #hematology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Lacrimal swelling • Skin ... Hypocomplementemia • Can cause ... amyloidosis, PAH Skin ... Nephrogenic DI Hematologic ... Cryoglobulinemia (4%-12%), Raynaud
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
) • Anti-Mi2 (skin ... joint pain and Raynaud ... aspiration > 50% of pts ... • Myositis • Raynaud ... statins - probably caused