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diagnosis differential rheumatology dermatology algorithm pathophysiology vasculitis alkaline alp arterial autoimmune behcet brain childhood clinical disease embolism erythematosus eschar hepatology
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent Multiple Ring-Enhancing Lesions: • Toxoplasmosis (CD4 < 100) • Other
CNS Ring-Enhancing ... + toxo IgG • CNS ... 30% present w/ CNS ... , may also see skin ... : • CNS Lymphoma
Vascular Skin Lesions - Differential Diagnosis Algorithm - Petechiae < 0.2 cm diameter - Purpura 0.2
Vascular Skin Lesions ... discolorations of skin ... #Vasculitis #SkinRash ... #dermatology #Differential ... Diagnosis #Algorithm #causes
Childhood Immunization Schedule: Why we immunize • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
replicates within CNS ... & CNS invasion ... CNS and hematologic ... that persists as skin ... lesions -> Vesicular
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
et diutinum Neurologic ... Scleromyxedema (CNS ... +PNS+GI+Endocrine ... Paraproteinemias #Hematology ... Differential #Diagnosis #Oncology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
injury) • Neurologic ... basal ganglia, CNS ... meningitis), MCC CNS ... and diplopia) • Vascular ... collaboration • CNS
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
purple, hemorrhagic skin ... lesions that result ... Etiology: • Vascular ... deficiencies - PNH ... Differential #Diagnosis #hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Testosterone - Coumadin skin ... atherosclerotic lesions ... coagulation and other causes ... pathophysiology #hematology ... differential #diagnosis #vascular
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... reddish-purple lesions ... Disruptions in vascular ... blood test • Serology ... cryoglobulins • Skin
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
pulse deficits vascular ... , neurologic, and ... cognitive impairment, neurologic ... tract, and often causes ... chorioretinitis, CNS
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
involvement • 30%: CNS ... leukostasis syndrome: CNS ... CLL -> Invade Skin ... #Leukemia #Hematology ... #Oncology #Diagnosis
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