13 results
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent
Multiple Ring-Enhancing Lesions:
 • Toxoplasmosis (CD4 < 100)
 • Other
CNS Ring-Enhancing ... + MRI lesions + ... toxo IgG • CNS ... 30% present w/ CNS ... @AnnKumfer #CNS
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Demyelinating Syndrome ... autoantibodies that will cause ... thrombosis and/or blood-brain ... Erythematosus #SLE #CNS
BEE Syndromes - Non-inflammatory Causes

Immune-mediated conditions affecting the Brain, Eye, and Ear

Visual or auditory symptoms in
Non-inflammatory Causes ... affecting the Brain ... nervous system (CNS ... Non-inflammatory causes ... neuropathy (LHON) plus MRI
Hypertrophic Pachymeningitis - Differential Diagnosis Framework

Pachymeningitis is a rare condition that causes areas of a layer
condition that causes ... spinal cord and brain ... Neurosyphilis • CNS ... pachymeningitis • CNS ... sagging syndrome
Leigh Syndrome 
History: 19-month-old girl with hypotonia, developmental 
delay, failure to thrive, and bilateral optic disc
Leigh Syndrome ... patterns (this case ... #Clinical #MRI ... #Brain #Diagnosis ... #Radiology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
involvement • 30%: CNS ... : CNS manifestations ... , hypoxia, CXR - ... • Tumor lysis syndrome ... #Leukemia #Hematology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
blisters containing pus ... involve anterior chest ... Rule out other causes ... - MRI: inflammation ... diagnosis #management
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Pulmonary Renal Syndromes ... Pulmonary Renal Syndromes ... recent DAN) • EMG/NCS ... Goodpasture's cause ... differential #diagnosis #management
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Parotid swelling CNS ... nervous system (CNS ... • 8%-27% for CNS ... Nephrogenic DI Hematologic ... Diagnosis #Management
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
that results in CNS ... • Infectious causes ... ruled out • Brain ... brain and/or optic ... Myelitis #diagnosis #management