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diagnosis rheumatology differential neurology bee dermatology erythematosus lesions lupus noninflammatory ringenhancing sapho sjogrens sle syndromes treatment vasculitis
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Demyelinating Syndrome ... autoantibodies that will cause ... Erythematosus #SLE #CNS ... #management #treatment
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent Multiple Ring-Enhancing Lesions: • Toxoplasmosis (CD4 < 100) • Other
CNS Ring-Enhancing ... + MRI lesions + ... toxo IgG • CNS ... 30% present w/ CNS ... @AnnKumfer #CNS
BEE Syndromes - Non-inflammatory Causes Immune-mediated conditions affecting the Brain, Eye, and Ear Visual or auditory symptoms in
Non-inflammatory Causes ... affecting the Brain ... central nervous system ... (CNS) involvement ... neuropathy (LHON) plus MRI
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Parotid swelling CNS ... (CNS): demyelinating ... • 8%-27% for CNS ... Nephrogenic DI Hematologic ... Diagnosis #Management
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
blisters containing pus ... involve anterior chest ... Rule out other causes ... - MRI: inflammation ... diagnosis #management
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
oligoclonal bands • MRI ... tract, and often causes ... vasculitis • Behcet syndrome ... chorioretinitis, CNS ... vasculitis • Cogan syndrome
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