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diagnosis differential rheumatology neurology treatment aids cerebritis clinical crypto cryptococcal dermatology erythematosus hiv infections infectiousdiseases lesions lung lupus meningitis prs
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent Multiple Ring-Enhancing Lesions: • Toxoplasmosis (CD4 < 100) • Other
CNS Ring-Enhancing ... + MRI lesions + ... toxo IgG • CNS ... 30% present w/ CNS ... @AnnKumfer #CNS
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Demyelinating Syndrome ... autoantibodies that will cause ... thrombosis and/or blood-brain ... Erythematosus #SLE #CNS
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Syndromes - OnePager ... Renal Syndromes ... recent DAN) • EMG/NCS ... Goodpasture's cause ... #diagnosis #management
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Parotid swelling CNS ... nervous system (CNS ... • 8%-27% for CNS ... Nephrogenic DI Hematologic ... Diagnosis #Management
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
blisters containing pus ... involve anterior chest ... Rule out other causes ... - MRI: inflammation ... diagnosis #management
Lung Infections in HIV - Differential Diagnosis Framework Disease by CD4 Count: Any CD4 Count: • Mycobacterium tuberculosis,
Pneumonia: • 3 syndromes ... of a "flu-like syndrome ... Lymphadenopathy, CNS ... factor • May cause ... Infections #HIV #AIDS #pulmonary
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
oligoclonal bands • MRI ... tract, and often causes ... vasculitis • Behcet syndrome ... chorioretinitis, CNS ... vasculitis • Cogan syndrome
Cryptococcal meningitis on T2 MRI 30 M from sub-Saharan Africa presents w/ progressive Headache x1 mo, +neck
low glucose) CNS ... of prior silent pulmonary ... Nausea & vomiting ... #Brain #clinical ... #radiology
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