28 results
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... Osteomyelitis / Septic Arthritis ... • Differentiate ... #diagnosis #causes ... #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... hemorrhagic skin lesions ... Drug induced - Bone ... deficiencies - PNH ... #Diagnosis #hematology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
basal ganglia, CNS ... meningitis), MCC CNS ... Behcet disease) Differential ... Syndrome #diagnosis #management ... signs #symptoms #rheumatology
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
Causes of Knee Effusions ... - Differential ... - Aneurysmal bone ... #differential # ... diagnosis #msk #
Childhood Immunization Schedule: Why we immunize
 • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
asymmetric reduction in tone ... invade URT & via hematologic ... altered LOC; septic arthritis ... CNS and hematologic ... persists as skin lesions
Focal Periphyseal Edema (FOPE lesion) - MSK Radiology
Imaging Findings:
 • Arrows identifying the characteristic edema-like signal
) - MSK Radiology ... physeal fusion and bone ... (save $$) Differential ... • Bone contusion ... #diagnosis #msk
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
blisters containing pus ... Pustular skin lesions ... nonerosive inflammatory arthritis ... Rule out other causes ... #diagnosis #management
Gout (Gouty Arthritis) - MSK Radiology
Imaging Findings:
 • Eccentric soft-tissue densities surrounding the third proximal interphalangeal
Gout (Gouty Arthritis ... ) - MSK Radiology ... Differential diagnosis ... • PVNS/Giant Cell ... #rheumatology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
Arterial Thrombosis - Differential ... atherosclerotic lesions ... coagulation and other causes ... pathophysiology #hematology ... #differential #
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
juvenile idiopathic arthritis ... nervous system (CNS ... juvenile idiopathic arthritis ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology