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diagnosis neurology rheumatology erythematosus lupus ringenhancing syndrome systemic algorithm bee behcet cerebritis dermatology disease gravis myasthenia myelitis noninflammatory nonpalpable palpable
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent Multiple Ring-Enhancing Lesions: • Toxoplasmosis (CD4 < 100) • Other
CNS Ring-Enhancing ... + toxo IgG • CNS ... 30% present w/ CNS ... : • CNS Lymphoma ... #Brain #differential
Algorithm for evaluating multiple ring-enhancing lesions in immunocompetent (HIV negative) #ringenhancing #lesions #cns #brain #diagnosis #differential #algorithm
ring-enhancing lesions ... #cns #brain #diagnosis ... #differential # ... algorithm #causes ... #radiology #neurology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... autoantibodies that will cause ... thrombosis and/or blood-brain ... #CNS #neurology ... cerebritis #diagnosis #management
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... hemorrhagic skin lesions ... Associated - SLE ... , Sjogren's ... #Diagnosis #hematology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
basal ganglia, CNS ... meningitis), MCC CNS ... Behcet disease) Differential ... collaboration • CNS ... Syndrome #diagnosis #management
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... Parotid swelling CNS ... nervous system (CNS ... • 8%-27% for CNS ... phenomenon (16%) MSK
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
that results in CNS ... or Sjogren's ... • Infectious causes ... Myelitis #diagnosis #management ... #neurology #differential
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
papulosquamous lesions ... permanent alopecia Differential ... dermatomyositis, Sjogren ... • May involve PNS ... and CNS • Headache
BEE Syndromes - Non-inflammatory Causes Immune-mediated conditions affecting the Brain, Eye, and Ear Visual or auditory symptoms in
Non-inflammatory Causes ... affecting the Brain ... nervous system (CNS ... LHON) plus MRI lesions ... noninflammatory #differential
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
Autoimmune: thyroid, Sjogren ... rheumatoid arthritis, SLE ... life-threatening Differential ... Myotonic dystrophy - Brain ... Gravis #diagnosis #management
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